WebSafety issues regarding the potential risk of statins and incident rheumatoid arthritis (RA) have been raised, but the existing data are largely based on Caucasian populations, and continue to have biases and require further validation in Asian populations. Here, we aimed to verify the risk of RA depending on the duration of previous statin use and statin types … Web20 jul. 2024 · Secondary endpoints were safety parameters: drug discontinuation, statin-associated muscle symptoms and alanine aminotransferase level increase. Results. A …
Lipophilic Statins Not Associated With Significant Increase in …
Web1 mei 2024 · The predominantly lipophilic statins (simvastatin, fluvastatin, pitavastatin, lovastatin and atorvastatin) can easily enter cells, whereas hydrophilic statins … WebStatins, also known as HMG-CoA reductase inhibitors, ... Some researchers have suggested hydrophilic statins, such as fluvastatin, rosuvastatin, and pravastatin, are less toxic than lipophilic statins, such as atorvastatin, lovastatin, and simvastatin, ... fishman keith merrow
Statin Lipophilicity and the Risk of Incident Heart Failure
WebStatins such as lovastatin, simvastatin, atorvastatin, and cerevastatin are lipophilic in nature and, as such, diffuse across membranes and thus are highly cell permeable. Hydrophilic statins such as pravastatin are more polar, such that they require specific cell surface transporters for cellular uptake. K. Web11 mrt. 2024 · In addition, the risk of adverse effects may be increased when statins are taken with the following medications: Sporanox (itraconazole) Erythrocin (erythromycin) … Web12 jul. 2024 · Dave C, Winterstein A, Park H, Cook R, and Hartzema A. Comparative risk of lipophilic and hydrophilic statins on incident depression: A retrospective cohort study. J Affect Disord . 2024;238:542-546. can collagen thicken hair