WebAug 6, 2024 · Inactivated Sendai virus particle (or hemagglutinating virus of Japan envelope; HVJ-E) has been previously reported to possess antitumour properties that … WebInactivated Sendai Virus Envelope Vector (HVJ-E) with Intrinsic Anti-Tumor Activities Yasufumi Kaneda1, Eiji Kiyohara1,2, Toshimitsu Itai3 and Toshihiro Nakajima3 1Division …
Inactivated Sendai Virus Induces ROS-dependent ... - ScienceDirect
WebJan 1, 2016 · Inactivated Sendai virus (hemagglutinating virus of Japan; HVJ) envelope (HVJ-E) induces anticancer immunity and cancer cell-selective apoptosis through the recognition of viral RNA genome fragments by retinoic acid-inducible gene-I (RIG-I). Here, we discovered that the “copy-back” type of defective-interfering (DI) particles that exist in the … WebApr 1, 1995 · Heat-inactivated Sendai virus can enter multiple MHC class I processing pathways and generate cytotoxic T lymphocyte responses in vivo We have earlier … greem handyshop rodgau
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HVJ-E was manufactured at GenomIdea Inc. (Osaka, Japan). HVJ was irradiated by the treatment with β-propiolactone and ultraviolet irradiation, which caused the alkylation and the fragmentation of the RNA genome. HVJ-E was purified by four steps of column chromatography, stabilized by lyophilization and … See more This study was a single-arm, open-label, single-center, phase I/II study of HVJ-E in patients with CRPC who were docetaxel resistant or could not receive docetaxel treatments. The primary end points were to evaluate safety and … See more Eligible patients had to have CRPC and be docetaxel resistant or unable to receive docetaxel treatment and have a prostate in which HVJ-E could be administered. Patients were … See more Patients were monitored in hospital from day 1 to day 14 and at each outpatient visit on days 21 and 28 of each cycle. The National Cancer Institute’s Common Terminology Criteria for Adverse Events version 4.0 was used … See more A 3+3 design was used to determine the maximum tolerated dose of HVJ-E administration. HVJ-E was administered directly to the … See more WebWe have already reported that the inactivated Sendai virus (hemagglutinating virus of Japan; HVJ) envelope (HVJ-E) has multiple anticancer effects, including induction of … WebDec 1, 2014 · We previously reported that inactivated Sendai virus (hemagglutinating virus of Japan; HVJ) envelope (HVJ-E) activates anti-tumor immunity and induces cancer cell … greem boy star ocean till the end of time