Cisplatin and hydration

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August undefined, 2024

WebJun 27, 2024 · 摘要Aims: To ascertain the efficacy and toxicity of cisplatin in combination with adriamycin for patients with metastatic and/or locoregional recurrent nasopharyngeal carcinoma. Patients and Methods: A phase II trial combining cisplatin and adriamycin was conducted in 15 patients with metastatic nasopharyngeal carcinoma. WebIntroduction: Cisplatin, a platinum-based antineoplastic agent, is the cornerstone for the treatment of many malignancies. Nephrotoxicity is the primary dose-limiting toxicity, …

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WebDec 16, 2024 · IntroductionCisplatin, a chemotherapeutic drug, is widely used for the treatment of various malignant tumors with good effects. However, cisplatin-induced … WebFeb 16, 2016 · In this study, we assessed nephrotoxicity in daily practice among patients treated with high-dose cisplatin (100 mg/m 2 on days 1, 22, and 43), concurrently with chemoradiotherapy (CCRT) and the impact on treatment modifications. Methods: 208 patients with advanced-stage malignancies of the head and neck region were evaluated. iphone 8s+

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WebJun 23, 2024 · Depending on the protocol, 1 - 2 litres pre-hydration. The patient must have urinated a litre minimum before we proceed. Our cisplat goes in 250 mls usually giving us a final volume of 340 mls. We used to pass Mannitol concurrently but that's now been … http://school.freekaoyan.com/hongkong/cuhk/2024/06-27/1498578834645114.shtml Web17 hours ago · The number of drug shortages is forecast to reach a record level this year, imperiling patients. Cancer drugs in short supply include injectable cisplatin, methotrexate, and fluorouracil. Stocksy ... iphone 8 rockhampton

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Staying Hydrated After Moderate to High-Dose Cisplatin

WebJun 1, 2014 · Hydration with normal saline is recommended for preventing cisplatin nephrotoxicity, but there is no clear data on the appropriate amount and duration of hydration. Furthermore, there is no consensus on a standard cisplatin hydration regimen. WebCisplatin for injection is a highly emetogenic antineoplastic agent; premedicate with anti-emetic agents; without antiemetic therapy, marked nausea and vomiting occur in almost … iphone 8p 尺寸图 iphone 8 says sos only

"WebSep 4, 2013 · Cisplatin was administered with pre- and post-hydration containing 10 mEq of potassium chloride in 500 ml of fluid over a 60-min period. Immediately before the administration of cisplatin, mannitol (20%, 200 ml) was administered as forced diuresis over 30 min. And magnesium sulfate (8 mEq) was added to pre-hydration. Results " - Cisplatin and hydration

Cisplatin and hydration

Nephrotoxicity and hydration management for cisplatin

WebThis regimen must be administered by a clinician trained in the use of chemotherapy, who should use independent medical judgment in the context of individual circumstances to make adjustments, as necessary. IV: intravenous; CBC: complete blood count; GFR: glomerular filtration rate. WebCisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, …

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WebIn conventional treatment regimens employing doses of cisplatin of less than 100 mg/m (2) in patients with normal renal function, pre- and post-hydration (3 l/m (2) at least 12 h pre-cisplatin and 24 h post-cisplatin) alone should be routinely used. WebJul 15, 2015 · Hydration is recommended to induce diuresis and reduce the concentration of cisplatin in the kidneys. Isotonic saline (0.9% sodium chloride) is recommended for hydration fluids, and many...

WebThe literature review identified 11 relevant studies with cisplatin doses between 50-100mg/m2 treating a range of malignancies. Total hydration volumes were between … WebSep 4, 2013 · Cisplatin labels with regard to hydration should accept short- and lower-volume hydration as an option based on the result of the present study. Funding. This …

WebFigure 1. An example of chemotherapy regimen: cisplatin and pemetrexed. - "Short hydration in chemotherapy containing cisplatin (≥75 mg/m2) for patients with lung cancer: a prospective study." WebApr 12, 2024 · AKI, present in 20–30% of patients’ cisplatin exposed, is usually non-oliguric. Moreover, urinalysis may detect glycosuria and a low-grade proteinuria. AKI-related cisplatin may also be associated with tubulopathies, such as Fanconi-like syndrome, hypomagnesemia, salt-loosing syndrome and distal renal tubular acidosis . Tubular …

WebApr 12, 2024 · Cisplatin is a platinum-based chemotherapy agent that currently used as front-line therapy in the treatment of various solid organ cancers, including head and neck, lung, testis, ovary, breast, bladder cancer and sarcoma [1–7]. The therapeutic effects of cisplatin are significantly improved by dose escalation.

WebOct 19, 2024 · This information will help you hydrate yourself to get ready for your cisplatin chemotherapy. Cisplatin can affect your kidneys. To keep your kidneys from getting damaged, you’ll need to drink plenty of liquids before you get cisplatin chemotherapy. iphone 8 rrpWebPretreatment hydration: Patients should be adequately hydrated before and for 24 hours after administration of cisplatin to ensure good urinary output and minimise nephrotoxicity. Hydration may be achieved by IV infusion of 2 litres of either sodium chloride IV infusion 0.9% or glucose-saline (e.g. glucose 4% in one-fifth sodium iphone 8 replace batteryWebCisplatin(cis-dichlorodiammineplatinum)–platinum coordination complex is an effective chemotherapy against a wide spectrum of tumors such as testicular, head and neck, ovarian, lung, cervical, and bladder cancers. Nephrotoxicity is the dose-limiting toxicity of cisplatin. Cisplatin induces the production of ROS iphone 8 rugged protective casesWebAug 16, 2024 · Fessi method, nanoprecipitation, thin-film hydration, microemulsion, emulsion polymerization, ultra-sonication, wet milling, spray drying, antisolvent precipitation, ionic gelation, solvent evaporation ... Like gemcitabine and cisplatin as chemotherapeutic medications, it inhibits the development of malignant cells with IC 50 ranging from ... iphone 8 remove screen time limitsWebSep 1, 2024 · Cisplatin Dosage and Administration Hydration and Anti-Emetic Treatment Patients treated with Cisplatin for injection must receive appropriate pre-treatment … iphone 8 remote management bypass freeWebDec 12, 2024 · You will need to make sure you are not dehydrated before, during, and after doses of this drug. Drink lots of noncaffeine liquids and have your blood work checked as you have been told by your doctor. This drug may cause nerve problems. These nerve problems can get worse the more times you get this drug. iphone 8 running slowWebCisplatin is a chemotherapy drug used to treat testicular, ovarian, bladder, head and neck, lung and cervical cancer. It may also be used to treat other cancers. It is best to read this information with our general information about chemotherapy and the … iphone 8 screen black but still on